Conclusion  In this fetal lamb model of CDH, tezosentan decreased pulmonary artery pressure but did not modify pulmonary blood flow. Endothelin may play a role in the regulation of pulmonary vascular tone in utero. Content Type Journal ArticleDOI 10.1007/s00383-010-2668-4Authors Eleuthère Stathopoulos, Department of Pediatric Surgery, Hospital Timone Enfant, Marseille, FrancePierre-Henri Rolland, School of Medicine, Mediterranean University, Marseille, FranceGéraldine Héry, Department of Pediatric Surgery, Hospital Timone Enfant, Marseille, FranceCatherine de Magnée, Department of Pediatric Surgery, Hospital Timone Enfant, Marseille, FranceOlivier Paut, Department of Anesthesiology, Intensive Care, Hospital Timone Enfant, Marseille, FranceEmmanuelle Couchot, Depar...