Conclusions  Endoscopic full-thickness plication using multiple Plicator implants can be used safely and effectively to improve GERD symptoms and reduce medication use. Content Type Journal ArticleDOI 10.1007/s00464-009-0490-7Authors D. von Renteln, Klinikum Ludwigsburg, Teaching Hospital of the Heidelberg University Department of Gastroenterology, Hepatology and Oncology Ludwigsburg GermanyI. Schiefke, University of Leipzig Department of Gastroenterology Leipzig GermanyK. H. Fuchs, Markuskrankenhaus Department of Surgery Frankfurt GermanyS. Raczynski, University of Leipzig Department of Gastroenterology Leipzig GermanyM. Philipper, EVK Medizinische Klinik Duesseldorf GermanyW. Breithaupt, Markuskrankenhaus Department of Surgery Frankfurt GermanyK. Caca, Klinikum Ludwig...